Gene Information
|
Gene Name
|
A20/TNFAIP3
|
|
Species
|
Human
|
|
Gene Length
|
2373 bp
|
|
Product Feature
|
Full length Clone DNA of Human tumor necrosis factor, alpha-induced protein 3.
|
|
Sequence Signature
|
Identical with the Gene Bank Ref. ID sequence.
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Plasmid Information
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Vector
|
pGEM-T Vector
|
|
Sequencing Primer
|
SP6 and T7 or M13-47 and RV-M
|
|
Quality Control
|
The plasmid is confirmed by full-length sequencing.
|
|
Bacterial Screening Resistance
|
Ampicillin
|
Background
TNFAIP3, also named A20, uses ubiquitin-related functions to regulate immune activation, deficiency of which is highly related to autoimmune disease. Mutations in tumor necrosis factor alpha-induced protein 3 (TNFAIP3), a key player in the negative feedback regulation of nuclear factor-kappaB signaling, have recently been recognized as leading to early onset autoinflammatory and autoimmune syndrome.
![A20/TNFAIP3 cDNA ORF Clone in Cloning Vector, Human [BY-P-13772]](http://30712400.s21i.faiusr.com/4/1/ABUIABAEGAAgwIe-ogYoyP7n_AMwmwQ46AU!400x400.png)
